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GLP-3 Retatrutide

Third generation of weight loss medication.

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How did average weight loss go from 8 to 29 percent?

GLP-3 mimics three biological signals:
appetite, sugar and fat burning.

Four medications. One decade.
Each generation targets more of the body’s metabolic pathways.

Catalyst GLP-3 RT 10 mg vial
Signal 1
Appetite ControlGLP-1
Full faster and reduces hunger
Signal 2
Metabolic SupportGIP
Process sugars and fats more efficiently
Signal 3
Energy ReleaseGlucagon
Uses stored fat as energy
2025
GlucagonGIPGLP-1
Retatrutide
28.7%Average Weight Loss
2022
GIPGLP-1
Mounjaro / Zepbound
22.5%Average Weight Loss
2021
GLP-1
Ozempic / Wegovy
15%Average Weight Loss
2015
GLP-1
Saxenda
8%Average Weight Loss

What the research shows
About GLP-3

Body Composition
29%Average weight loss
76%Improvement in joint pain
1 in 8Reported complete pain relief
Cardiovascular
14-ptDrop in blood pressure
27%Drop in non-HDL cholesterol (Harmful type)
41%Reduction in triglycerides (Blood fats)
Metabolic
86%Average liver fat reduction
93%Saw liver fat return to normal
71%Drop in fasting insulin
GLP-3 RT

Three targets. One peptide

  • GLP-1 Regulates the hunger signal
  • GIP Regulates how the body processes fat and sugar
  • Glucagon Signals the body to use stored energy
Research use onlyGet GLP-3 →
For educational purposes only. Not medical advice. Consult a healthcare professional